Semaglutide vs Tirzepatide vs Retatrutide – Price Comparison 2026

By Peptideals · Updated March 2026

⚠️ For research purposes only. Not for human consumption.

GLP-1 and GLP-1/GIP research peptides are among the most searched compounds in 2026. Prices vary significantly across vendors and formulations. Here's how Semaglutide, Tirzepatide, and Retatrutide compare on price across our 24+ vendor network.

Price Overview by Compound

Semaglutide

GLP-1 receptor agonist. Most widely available. Generally the most affordable of the three.

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Tirzepatide

GLP-1 / GIP dual agonist. More potent than Semaglutide. Prices have dropped significantly in 2026.

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Retatrutide

GLP-1 / GIP / glucagon triple agonist. Newest compound, premium pricing but becoming more accessible.

Compare Retatrutide prices →

Which Is the Best Value?

On a per-mg basis, Semaglutide is typically the most affordable. Tirzepatide offers more potency per mg, making it competitive on a dose-adjusted basis. Retatrutide is the newest and priciest, but prices have been falling as more vendors stock it.

The best strategy is to check current live prices using Peptideals — prices shift weekly as vendors run sales and adjust inventory.

See Live Prices for All GLP-1 Peptides

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